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Syndax Pharmaceuticals Inc (OQ:SNDX)

Business Focus: Biotechnology & Medical Research

Sector:  Healthcare Industry:  Biotechnology & Medical Research
 
See Regulatory Filings on SEC
Company Contact
Address: 35 Gatehouse Drive, Building D, Floor 3
WALTHAM MA 02451
Tel: N/A
Website: https://syndax.com
IR: See website
Key People
Neil Gallagher
President, Head of Research and Development
Michael A. Metzger
Chief Executive Officer, Director
Keith A. Goldan
Chief Financial Officer
Luke J. Albrecht
General Counsel, Secretary
Steven Closter
Chief Commercial Officer
Catherine Madigan
Chief Medical Officer
Business Overview
Syndax Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing pipeline of cancer therapies. Its product candidates include revumenib, and axatilimab. It is developing revumenib, a potent, selective, small molecule inhibitor of the menin-MLL binding interaction for the treatment of KMT2A rearranged also known as mixed lineage leukemia rearranged, acute leukemias including acute lymphoblastic leukemia and acute myeloid leukemia (AML), and necleophosmin 1, also known as NPM1, mutant A. It is also exploring the use of revumenib as a treatment in solid tumors, specifically its activity in metastatic colorectal cancer. It is also developing axatilimab, a monoclonal antibody that blocks the colony stimulating factor 1 receptor (CSF-1R) in chronic graft-versus-host disease (cGVHD), as well as idiopathic pulmonary fibrosis. Entinostat is its oral, small molecule product candidate that has direct effects on both cancer cells and immune regulatory cells.
Financial Overview
For the three months ended 31 March 2024, Syndax Pharmaceuticals Inc revenues was not reported. Net loss increased 76% to $72.4M. Higher net loss reflects Pharmaceuticals segment loss increase of 73% to $79.5M. Basic Earnings per Share excluding Extraordinary Items decreased from -$0.59 to -$0.85.